If England do manage to navigate a way out of Group B then they would most likely face India in Dubai, where spin has played a key role.
Carse was picked for the Champions Trophy despite missing the final two ODIs of England’s tour of India because of the toe issue earlier this month.
The injury required stitches, which were removed shortly before the tournament began.
“We will have to wait and see,” England batter Joe Root told the BBC in Lahore.
“There is still a good way to go until the game, to find exactly what is up with Carsey. We will see how things pan out over the next few days.”
Carse has impressed for England this winter after making his Test debut against Pakistan in October.
He has a contract worth £100,000 to play for Sunrisers Hyderabad in the Indian Premier League, which begins next month.